The surgical results of 354 patients with gastric with gastric adenocarcinoma treated at the Department of Surgery, Kangnam Sarced Heart Hospital, Hallym University from 1984 to 1993 were reported.
@EN The survival rate of the 354 patients was compared with reference to categories of prognostic factors(univariate analysis) and significant factors affecting survival were identified by multivariate analysis using the Cox's proportional hazard
model.
The resection rate was 93.5% and the operative mortality within 1 months was 2.5%. The 5-year survival rates were 49.2% for the entire group of patients, 52.0% for patients who under went resection, 72.3% for patients who underwent curative
resection,
and 18.4% for patients who underwent palliative resection. The 5-year survival rates according to the TNM stage were 85.4% for stage I, 56.0% for stage Ⅱ, 38.2% for stage Ⅲ, and 10.3% for stage Ⅳ.
Univariate analyses showed a significant difference in survival in relation to age, primary tumor factor(T), regional lymph node factor(N), distant metastasis factor(M), macroscopic type, size of tumor, type of operation, TNM stage and curability
of
surgery. Multivariate analysis using the Cox's proportional hazard model in a stepwise fashion identified a final set of three significant variables: curability of surgery(P=0.0002), TNM stage(P=0.0007), and macroscopic type(P=0.0008).
These results suggest that continuing efforts to increase rate of less advanced cancers and curative resection with systematic lymph node dissection in advanced cancers are necessary for an improvement of the end results of surgical treatment.
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